One of the signs of aging is the appearance of facial wrinkles. Long-term stress and ultraviolet exposure can induce premature facial wrinkles. In order to eliminate annoying facial wrinkles, surgical methods have been used in the past. In the future, collagen injections will not be used. As expected. Nowadays, there is a scientific alternative method, namely biological wrinkle removal, which can avoid the pain of surgery and many adverse complications. This biological wrinkle removal method uses local intramuscular injection of botulinum toxin type A to make facial expressions It produces reversible and transient paralysis of the muscles, thereby significantly reducing facial wrinkles and rejuvenating the person's youthful beauty.